Category:FLI - Revision history

Adm: /* {{Bilingual|生合成|Biosynthesis}} */

2011-06-04T07:26:48Z

‎{{Bilingual|生合成|Biosynthesis}}

Adm: /* {{Bilingual|生合成|Biosynthesis}} */

2011-06-04T07:25:27Z

‎{{Bilingual|生合成|Biosynthesis}}

Adm at 03:14, 24 September 2010

2010-09-24T03:14:08Z

Adm: /* {{Bilingual|代表例|Representative Names}} */

2010-08-19T04:50:36Z

‎{{Bilingual|代表例|Representative Names}}

Adm: /* {{Bilingual|代表例|Representative Names}} */

2010-08-19T03:33:32Z

‎{{Bilingual|代表例|Representative Names}}

Adm: /* {{Bilingual|耳にする名前|Familiar Names}} */

2010-08-19T03:07:30Z

‎{{Bilingual|耳にする名前|Familiar Names}}

Adm at 08:49, 18 August 2010

2010-08-18T08:49:00Z

Adm: /* Overview */

2010-03-10T16:00:14Z

‎Overview

Adm: /* Biosynthesis */

2010-01-08T14:19:12Z

‎Biosynthesis

Adm: /* Overview */

2010-01-08T14:14:38Z

‎Overview

@@ Line 107: / Line 107: @@
 | IFS
 | isoflavone synthase
-| cytochrome P450 oxygenase family <ref>Akashi T, Aoki T, Ayabe S: Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice. Plant Physiol 1999 121:821-828</ref>
+| cytochrome P450 oxygenase family <ref>Akashi T, Aoki T, Ayabe S: Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice. Plant Physiol 1999 121:821-828</ref><ref>Steele CL, Gijzen M, Qutob D, Dixon RA: Molecular characterization of the enzyme catalyzing the aryl migration reaction of isoflavonoid biosynthesis in soybean. Arch Biochem Biophys 1999 367: 146–150</ref>
 * CYP93C subfamily in Fabaceae<ref>Ayabe S, Akashi T (2006) ''Phytochem Rev'' 5(2-3), 271-282</ref>
 * ''IgIFS1'' in German iris (Iridaceae) shows low similarity (< 35%) with other P450<ref>Akashi T (2011) Proceedings of Biosynthetic Machinary (in Japanese)</ref>
 | Use both liquiritigenin and naringenin as substrates to produce genistein and daidzein, respectively.
 |-

@@ Line 108: / Line 108: @@
 | isoflavone synthase
 | cytochrome P450 oxygenase family <ref>Akashi T, Aoki T, Ayabe S: Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice. Plant Physiol 1999 121:821-828</ref>
 <ref>Steele CL, Gijzen M, Qutob D, Dixon RA: Molecular characterization of the enzyme catalyzing the aryl migration reaction of isoflavonoid biosynthesis in soybean. Arch Biochem Biophys 1999 367: 146–150</ref>
 <ref>Jung W, Yu O, Sze-Mei CL, O’Keefe DP, Odell J, Fader G, McGonigle B: Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes. Nat Biotechnol 2000 18: 208–213</ref>

@@ Line 51: / Line 51: @@
 メディカルパンはアルファルファ([[Species:Medicago|''Medicago sativa'']])やクローバー([[Species:Trifolium|Trifolium spp.]])が微生物の感染に対抗して生産する防御物質として知られる。
 }}
 <references/>

@@ Line 46: / Line 46: @@
 {{Twocolumn|
 [[FLIA1AGS0001|Daidzin]] is its glycosylated form in soy beans. Daidzein (aglycon) is contained in fermented beans.
-Medicarpin is the major phytoalexin in alfalfa ([[Species:Medicago|''Medicago sativa'']]), synthesized by bacterial infection.
+Medicarpin is the major phytoalexin in alfalfa ([[Species:Medicago|''Medicago sativa'']]) and clover ([[Species:Trifolium|Trifolium spp.]]), synthesized by bacterial infection<ref>Guo L, Dixon RA, Paiva NL (1994) Conversion of vestitone to medicarpin in alfalfa (Medicago sativa L.) is catalyzed by two independent enzymes. Identification, purification, and characterization of vestitone reductase and 7,2'-dihydroxy-4'-methoxyisoflavanol dehydratase. ''J Biol Chem'' 269:22372-22378</ref>.
+|
 大豆に含まれるのは、[[FLIA1AGS0001|ダイジン]]というダイゼインの配糖体。豆を醗酵させるとアグリコンであるダイゼインになる。
-メディカルパンはアルファルファ([[Species:Medicago|''Medicago sativa'']])が微生物の感染に対抗して生産する防御物質として知られる。
+メディカルパンはアルファルファ([[Species:Medicago|''Medicago sativa'']])やクローバー([[Species:Trifolium|Trifolium spp.]])が微生物の感染に対抗して生産する防御物質として知られる。
 }}
 <references/>

@@ Line 41: / Line 41: @@
 | [[FLIAAANS0001|genistein]]<br/>[[Image:FLIAAANS0001.png|120px]]
 | [[FLIE1ANS0001|coumestrol]]<br/>[[Image:FLIE1ANS0001.png|120px]]
-| [[FLID1ANS0001|Medicarpin]]<ref>The major phytoalexin in alfalfa (''Medicago sativa'')</ref><br/>[[Image:FLID1ANS0001.png|120px]]
+| [[FLID1ANS0001|Medicarpin]]<br/>[[Image:FLID1ANS0001.png|120px]]
 |}
 <references/>

@@ Line 36: / Line 36: @@
 <references/>
-==={{Bilingual|耳にする名前|Familiar Names}}===
+==={{Bilingual|代表例|Representative Names}}===
-<div style="column-count:2; -moz-column-count:2;">
+{| style="vertical-align:top"
-* [[FLIA1ANS0002|Daidzein]]
+| [[FLIA1ANS0002|daidzein]]<br/>[[Image:FLIA1ANS0002.png|120px]]
-* [[FLIAAANS0001|Genistein]]
+| [[FLIAAANS0001|genistein]]<br/>[[Image:FLIAAANS0001.png|120px]]
-* [[FLID1ANS0001|Medicarpin]] ... The major phytoalexin in alfalfa (''Medicago sativa'').
+| [[FLIE1ANS0001|coumestrol]]<br/>[[Image:FLIE1ANS0001.png|120px]]
-</div>
+| [[FLID1ANS0001|Medicarpin]]<ref>The major phytoalexin in alfalfa (''Medicago sativa'')</ref><br/>[[Image:FLID1ANS0001.png|120px]]
 =={{Bilingual|生合成|Biosynthesis}}==

@@ Line 3: / Line 3: @@
 {{Hierarchy|{{PAGENAME}}}}
 {| class="wikitable" border="1" cellspacing="0"
   |-
@@ Line 20: / Line 21: @@
   |FLIJ||[[:Category:FLIJ|alpha-Methoxynbenzoin]]<br>[[Image:Flij.png|90px]]
   |}
 {{Twocolumn|
@@ Line 37: / Line 36: @@
 <references/>
-===Familiar Names <small>耳にする名前</small>===
+==={{Bilingual|耳にする名前|Familiar Names}}===
 <div style="column-count:2; -moz-column-count:2;">
 * [[FLIA1ANS0002|Daidzein]]
@@ Line 44: / Line 43: @@
 </div>
-==Biosynthesis==
+=={{Bilingual|生合成|Biosynthesis}}==
 {{Twocolumn|
@@ Line 102: / Line 101: @@
 <references/>
-==Database statistics データベース統計==<!--- see FL1--->
+=={{Bilingual|データベース統計|Database statistics}}==<!--- see FL1--->
 {{#def:FLI|{{#SearchTitle:FLI|}}}}
 {{#def:rFLI|{{#SearchLine:&&FLI|Reference}}}}

@@ Line 26: / Line 26: @@
 The discovery of isoflavonoid was in 1842, when Reinsch and Hlasiwetz obtained ononin from the roots of spiny restharrow ([[Species:Ononis|''Ononis spinosa'' L.]])<ref>Reinsch H, ''Repert. Pharm.'' 26:12-31, 1842; Reinsch H, ''Repert. Pharm.'' 28:18-25, 1842; Hlasiwetz H, ''J. Prakt. Chem.'' 65:419-450, 1855; Hlasiwetz H, ''Sitzungsber. Kais. Akad. Wiss. Wien, Math.-Naturwiss. Kl.'' 15:142-168, 1855</ref>. Its structure was later determined by [[Reference:Baker_W:Robinson_R:Simpson_NM:%2CJ._Chem._Soc.%2C1933%2C_%2C274|Baker et al.]] as [[FLIA1AGS0002|Formononetin 7-O-glucoside]] (1933). Since then, most isoflavonoids have been found in [[:Category:Fabaceae|Fabaceae]] (bean family).
 <br/>
-First isoflavonoid found in non-bean family was iridin from the rhizomes of [[Species:Iris|''Iris florentina'']] ([[:Category:Iridaceae|Iridaceae]])<ref>de Laire G and Tiemann F, ''Chem. Ber.'', 26:2010, 1893</ref>.  The first structural identification was [[FLIACANS0001|Prunetin]] from [[Species:Prunus|Prunus]] species in 1910 by [[Reference:Finnemore_H:%2CPharm._J.%2C1910%2C31%2C604|Finnemore]]. Major isoflavonoids in iris are isoflavones and their O-glycosides. In iris, isoflavonoids are produced only in the rhizomes except for a trace of coumaranochromones in leaves <ref>Iwashita T, Ootani S: Flavonoids of the genus Iris: structures, distribution and function (review). Ann. Tsukuba Bot. Gard. 17:147-183 (in Japanese)</ref>.
+First isoflavonoid found in non-bean family was [[FLIAEGGS0001|iridin]] from the rhizomes of [[Species:Iris|''Iris florentina'']] ([[:Category:Iridaceae|Iridaceae]])<ref>de Laire G and Tiemann F, ''Chem. Ber.'', 26:2010, 1893</ref>.  The first structural identification was [[FLIACANS0001|Prunetin]] from [[Species:Prunus|Prunus]] species in 1910 by [[Reference:Finnemore_H:%2CPharm._J.%2C1910%2C31%2C604|Finnemore]]. Major isoflavonoids in iris are isoflavones and their O-glycosides. In iris, isoflavonoids are produced only in the rhizomes except for a trace of coumaranochromones in leaves <ref>Iwashita T, Ootani S: Flavonoids of the genus Iris: structures, distribution and function (review). Ann. Tsukuba Bot. Gard. 17:147-183 (in Japanese)</ref>.
+|
 イソフラボノイドの発見は1842年まで遡り、ReinschとHlasiwetzが
@@ Line 32: / Line 32: @@
 その構造を[[FLIA1AGS0002|Formononetin 7-O-glucoside]]と同定したのは [[Reference:Baker_W:Robinson_R:Simpson_NM:%2CJ._Chem._Soc.%2C1933%2C_%2C274|Baker et al.]] たちです(1933)。以降、イソフラボノイドのほとんどは[[:Category:Fabaceae|マメ科]]に見出されてきました。
 <br/>
-マメ科以外からはじめて見つかったイソフラボノイドは、アヤメ([[Species:Iris|''Iris florentina'']], [[:Category:Iridaceae|Iridaceae]])の根茎から抽出されたiridinです。ただし初めて精製、構造が同定されたのは1910年の[[FLIACANS0001|プルネチン]] ([[Species:Prunus|Prunus]]属) です([[Reference:Finnemore_H:%2CPharm._J.%2C1910%2C31%2C604|Finnemore]])。アヤメにおける主なイソフラボノイドはイソフラボンとその配糖体です。アヤメでは葉に微量あるクマラノクロモンを除く全イソフラボノイドが根茎にあります。
+マメ科以外からはじめて見つかったイソフラボノイドは、アヤメ([[Species:Iris|''Iris florentina'']], [[:Category:Iridaceae|Iridaceae]])の根茎から抽出された[[FLIAEGGS0001|イリジン]]です。ただし初めて精製、構造が同定されたのは1910年の[[FLIACANS0001|プルネチン]] ([[Species:Prunus|Prunus]]属) です([[Reference:Finnemore_H:%2CPharm._J.%2C1910%2C31%2C604|Finnemore]])。アヤメにおける主なイソフラボノイドはイソフラボンとその配糖体です。アヤメでは葉に微量あるクマラノクロモンを除く全イソフラボノイドが根茎にあります。
 }}

@@ Line 54: / Line 54: @@
 {| style="text-align:center"
 |-
-| style="background:whitesmoke"| liquiritigenin
+| style="background:whitesmoke"| liquiritigenin<br/>[[Image:FL2F1ANS0001.png|70px]]
 | <br/>[[Image:Arrow00r35.png]]<br/>IFS
-| style="background:oldlace" | daidzein
+| style="background:oldlace" | daidzein<br/>[[Image:FLIA1ANS0002.png|70px]]
 | <br/>[[Image:Arrow00r35.png]]<br/>IOMT
-| style="background:oldlace" | formononetin
+| style="background:oldlace" | formononetin<br/>[[Image:FLIA1ANS0001.png|70px]]
 | <br/>[[Image:Arrow00r35.png]]<br/>I2'H + IFR
-| style="background:whitesmoke" | vestitone
+| style="background:whitesmoke" | vestitone<br/>[[Image:FLIB1LNS0002.png|70px]]
 | <br/>[[Image:Arrow00r35.png]]<br/>VR + DMID
-| style="background:mistyrose" | medicarpin
+| style="background:mistyrose" | medicarpin<br/>[[Image:FLID1ANS0001.png|70px]]
 |}