http://metabolomics.jp/mediawiki/index.php?action=history&feed=atom&title=Liquiritin 2026-05-17T11:46:55Z Revision history for this page on the wiki MediaWiki 1.19.1 http://metabolomics.jp/mediawiki/index.php?title=Liquiritin&diff=107990&oldid=prev 2011-01-07T08:14:07Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 08:14, 7 January 2011</td> </tr><tr><td colspan="2" class="diff-lineno">Line 11:</td> <td colspan="2" class="diff-lineno">Line 11:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>==Mass Spectral Data==</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>==Mass Spectral Data==</div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">Liquiritin fragmentation</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>{|</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>{|</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>| ''m/z'' 417 [M-H]&lt;sup&gt;-&lt;/sup&gt; || {{Overrightarrow|-glucose}}</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>| ''m/z'' 417 [M-H]&lt;sup&gt;-&lt;/sup&gt; || {{Overrightarrow|-glucose}}</div></td></tr> <tr><td colspan="2" class="diff-lineno">Line 22:</td> <td colspan="2" class="diff-lineno">Line 23:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|-</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|-</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>| {{Overrightarrow|retrocyclization}} || ''m/z'' 167</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>| {{Overrightarrow|retrocyclization}} || ''m/z'' 167</div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|}</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|}</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">Neoliquiritin fragmentation</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">{|</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| ''m/z'' 417 [M-H]&lt;sup&gt;-&lt;/sup&gt; || {{Overrightarrow|-glucose}}</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| ''m/z'' 255&#160; || &amp;rarr; the same as liquiritin</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|-</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| || {{Overrightarrow|retro Diels-Alder}} || ''m/z'' 297 (&lt;sup&gt;1,3&lt;/sup&gt;A&lt;sup&gt;-&lt;/sup&gt;)</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">{|</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| {{Overrightarrow|-CO}} || ''m/z'' 269</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|-</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| {{Overrightarrow|-CO2}} || ''m/z'' 253</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|}</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|}</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|}</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|}</div></td></tr> </table>

Adm http://metabolomics.jp/mediawiki/index.php?title=Liquiritin&diff=107989&oldid=prev 2011-01-07T08:12:31Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 08:12, 7 January 2011</td> </tr><tr><td colspan="2" class="diff-lineno">Line 11:</td> <td colspan="2" class="diff-lineno">Line 11:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>==Mass Spectral Data==</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>==Mass Spectral Data==</div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">{|</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| ''m/z'' 417 [M-H]&lt;sup&gt;-&lt;/sup&gt; || {{Overrightarrow|-glucose}}</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| ''m/z'' 255&#160; </ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">{|</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| {{Overrightarrow|retro Diels-Alder}} || ''m/z'' 135 (&lt;sup&gt;1,3&lt;/sup&gt;A&lt;sup&gt;-&lt;/sup&gt;)</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| {{Overrightarrow|-CO2}} || ''m/z'' 91</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|-</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| {{Overrightarrow|retro Diels-Alder}} || ''m/z'' 119 (&lt;sup&gt;1,3&lt;/sup&gt;B&lt;sup&gt;-&lt;/sup&gt;)</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|-</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">| {{Overrightarrow|retrocyclization}} || ''m/z'' 167</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|}</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">|}</ins></div></td></tr> </table>

Adm http://metabolomics.jp/mediawiki/index.php?title=Liquiritin&diff=107988&oldid=prev 2009-12-18T06:41:05Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 06:41, 18 December 2009</td> </tr><tr><td colspan="2" class="diff-lineno">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Metabolite</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Metabolite</div></td></tr> <tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>|SysName=<del class="diffchange diffchange-inline">4H</del>-<del class="diffchange diffchange-inline">1-Benzopyran-4-one, </del>2-[4-(<del class="diffchange diffchange-inline">.</del>beta<del class="diffchange diffchange-inline">.</del>-D-<del class="diffchange diffchange-inline">glucopyranosyloxy</del>)phenyl]-2,3-dihydro-7-hydroxy-<del class="diffchange diffchange-inline">, (2S)</del>-</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>|SysName=<ins class="diffchange diffchange-inline">(2S)</ins>-2-[4-(beta-D-<ins class="diffchange diffchange-inline">Glucopyranosyloxy</ins>)phenyl]-2,3-dihydro-7-hydroxy-<ins class="diffchange diffchange-inline">4H-1-benzopyran-4</ins>-<ins class="diffchange diffchange-inline">one</ins></div></td></tr> <tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>|Common Name=&amp;&amp;Liquiritin&amp;&amp;<del class="diffchange diffchange-inline">4H</del>-<del class="diffchange diffchange-inline">1-Benzopyran-4-one, </del>2-[4-(<del class="diffchange diffchange-inline">.</del>beta<del class="diffchange diffchange-inline">.</del>-D-<del class="diffchange diffchange-inline">glucopyranosyloxy</del>)phenyl]-2,3-dihydro-7-hydroxy-<del class="diffchange diffchange-inline">, (S)</del>-&amp;&amp; Liquiritin <del class="diffchange diffchange-inline">(6CI,7CI,8CI)</del>&amp;&amp; 4',7-Dihydroxyflavanone 4'-(<del class="diffchange diffchange-inline">.</del>beta<del class="diffchange diffchange-inline">.</del>-D-glucopyranoside)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(<del class="diffchange diffchange-inline">.</del>beta<del class="diffchange diffchange-inline">.</del>-D-glucoside)&amp;&amp; 7-Hydroxyflavanone 4'-O-glucoside&amp;&amp; Likviritin&amp;&amp; Liquiritoside</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>|Common Name=&amp;&amp;Liquiritin&amp;&amp;<ins class="diffchange diffchange-inline">(S)</ins>-2-[4-(beta-D-<ins class="diffchange diffchange-inline">Glucopyranosyloxy</ins>)phenyl]-2,3-dihydro-7-hydroxy-<ins class="diffchange diffchange-inline">4H</ins>-<ins class="diffchange diffchange-inline">1-benzopyran-4-one</ins>&amp;&amp;Liquiritin&amp;&amp; 4',7-Dihydroxyflavanone 4'-(beta-D-glucopyranoside)&amp;&amp;4',7-Dihydroxyflavanone 4'-(beta-D-glucoside)&amp;&amp;7-Hydroxyflavanone 4'-O-glucoside&amp;&amp;Likviritin&amp;&amp;Liquiritoside<ins class="diffchange diffchange-inline">&amp;&amp;</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|CAS=551-15-5</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|CAS=551-15-5</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|KNApSAcK=</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|KNApSAcK=</div></td></tr> </table>

Toyama http://metabolomics.jp/mediawiki/index.php?title=Liquiritin&diff=107987&oldid=prev 2009-12-08T00:47:41Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:47, 8 December 2009</td> </tr><tr><td colspan="2" class="diff-lineno">Line 7:</td> <td colspan="2" class="diff-lineno">Line 7:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|KNApSAcK=</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|KNApSAcK=</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>}}</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>}}</div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Glycyrrhizae Radix LC-MS]]</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>==Mass Spectral Data==</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>==Mass Spectral Data==</div></td></tr> </table>

Toyama http://metabolomics.jp/mediawiki/index.php?title=Liquiritin&diff=107986&oldid=prev 2009-12-08T00:22:03Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:22, 8 December 2009</td> </tr><tr><td colspan="2" class="diff-lineno">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Metabolite</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Metabolite</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|SysName=4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)-</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|SysName=4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)-</div></td></tr> <tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>|Common Name=4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (S)-&amp;&amp; Liquiritin (6CI,7CI,8CI)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(.beta.-D-glucopyranoside)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(.beta.-D-glucoside)&amp;&amp; 7-Hydroxyflavanone 4'-O-glucoside&amp;&amp; Likviritin&amp;&amp; Liquiritoside</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>|Common Name=<ins class="diffchange diffchange-inline">&amp;&amp;Liquiritin&amp;&amp;</ins>4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (S)-&amp;&amp; Liquiritin (6CI,7CI,8CI)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(.beta.-D-glucopyranoside)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(.beta.-D-glucoside)&amp;&amp; 7-Hydroxyflavanone 4'-O-glucoside&amp;&amp; Likviritin&amp;&amp; Liquiritoside</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|CAS=551-15-5</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|CAS=551-15-5</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|KNApSAcK=</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>|KNApSAcK=</div></td></tr> </table>

Toyama http://metabolomics.jp/mediawiki/index.php?title=Liquiritin&diff=107985&oldid=prev 2009-12-08T00:09:09Z

<p>New page: {{Hierarchy|{{PAGENAME}}}} {{Metabolite |SysName=4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)- |Common Name=4H-1-Benzopyran-4-one, 2-[4-(.b...</p> <p><b>New page</b></p><div>{{Hierarchy|{{PAGENAME}}}}<br /> <br /> {{Metabolite<br /> |SysName=4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)-<br /> |Common Name=4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (S)-&amp;&amp; Liquiritin (6CI,7CI,8CI)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(.beta.-D-glucopyranoside)&amp;&amp; 4',7-Dihydroxyflavanone 4'-(.beta.-D-glucoside)&amp;&amp; 7-Hydroxyflavanone 4'-O-glucoside&amp;&amp; Likviritin&amp;&amp; Liquiritoside<br /> |CAS=551-15-5<br /> |KNApSAcK=<br /> }}<br /> <br /> ==Mass Spectral Data==</div>

Toyama