Enzyme:2.3.3.10

Latest revision as of 06:00, 21 June 2009

acetyl-CoA:acetoacetyl-CoA C-acetyltransferase(thioester-hydrolysing, carboxymethyl-forming)
Systematic Name	acetyl-CoA:acetoacetyl-CoA C-acetyltransferase(thioester-hydrolysing, carboxymethyl-forming)
Common Name	hydroxymethylglutaryl-CoA synthase (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase(CoA-acetylating) 3-hydroxy-3-methylglutaryl CoA synthetase 3-hydroxy-3-methylglutaryl coenzyme A synthase 3-hydroxy-3-methylglutaryl coenzyme A synthetase

(S) -3-Hydroxy-3-methyl-glutaryl-CoA	<Mapping> AtomMap:BMFYB5CAa008$BMFYS2ESa001$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	4 ↔ 2 5 ↔ 1 11 ↔ 4 12 ↔ 5 13 ↔ 6 14 ↔ 7 15 ↔ 8 16 ↔ 9 17 ↔ 10 18 ↔ 11 19 ↔ 12 20 ↔ 13 21 ↔ 14 22 ↔ 15 23 ↔ 16 24 ↔ 17 25 ↔ 18 42 ↔ 35 43 ↔ 36 44 ↔ 38 45 ↔ 37 46 ↔ 39 47 ↔ 40 48 ↔ 41 49 ↔ 42 50 ↔ 43 51 ↔ 44 52 ↔ 45 53 ↔ 46 54 ↔ 47 55 ↔ 48

CoA	<Mapping> AtomMap:BMCCPUAPf023$BMFYS4ESa004$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] 3-oxobutanethioate
	1 ↔ 7 2 ↔ 8 3 ↔ 9 4 ↔ 10 5 ↔ 11 6 ↔ 12 7 ↔ 13 8 ↔ 14 9 ↔ 15 10 ↔ 16 11 ↔ 17 12 ↔ 18 13 ↔ 19 14 ↔ 20 15 ↔ 21 32 ↔ 38 33 ↔ 39 34 ↔ 41 35 ↔ 40 36 ↔ 42 37 ↔ 43 38 ↔ 44 39 ↔ 45 40 ↔ 46 41 ↔ 47 42 ↔ 48 43 ↔ 49 44 ↔ 50 45 ↔ 51

(S) -3-Hydroxy-3-methyl-glutaryl-CoA	<Mapping> AtomMap:BMFYB5CAa008$BMFYS4ESa004$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] 3-oxobutanethioate
	1 ↔ 1 2 ↔ 2 3 ↔ 3 6 ↔ 4

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+{{ {{NAMESPACE}}/Header}}
 {{Enzyme
 |ec={{PAGENAME}}
 |SysName=acetyl-CoA:acetoacetyl-CoA C-acetyltransferase(thioester-hydrolysing, carboxymethyl-forming)
 |names=&&hydroxymethylglutaryl-CoA synthase&&(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase(CoA-acetylating)&&3-hydroxy-3-methylglutaryl CoA synthetase&&3-hydroxy-3-methylglutaryl coenzyme A synthase&&3-hydroxy-3-methylglutaryl coenzyme A synthetase
+}}
+{{Enzyme/Reaction| reaction= (S)-3-Hydroxy-3-methyl-glutaryl-CoA + CoA = Acetyl-CoA + Acetoacetyl-CoA + H2O
+| list=
+&& BMFYB5CAa008$BMFYS2ESa001$0
+&& BMCCPUAPf023$BMFYS4ESa004$0
+&& BMFYB5CAa008$BMFYS4ESa004$0
 }}

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.3.3.10