Enzyme:2.3.3.13

Revision as of 09:00, 2 February 2009

acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase(thioester-hydrolysing, carboxymethyl-forming)
Systematic Name	acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase(thioester-hydrolysing, carboxymethyl-forming)
Common Name	2-isopropylmalate synthase 3-carboxy-3-hydroxy-4-methylpentanoate3-methyl-2-oxobutanoate-lyase (CoA-acetylating) alpha-isopropylmalate synthetase alpha-isopropylmalic synthetase

CoA	<Mapping> AtomMap:BMCCPUAPf023$BMFYS2ESa001$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	1 ↔ 4 2 ↔ 5 3 ↔ 6 4 ↔ 7 5 ↔ 8 6 ↔ 9 7 ↔ 10 8 ↔ 11 9 ↔ 12 10 ↔ 13 11 ↔ 14 12 ↔ 15 13 ↔ 16 14 ↔ 17 15 ↔ 18 32 ↔ 35 33 ↔ 36 34 ↔ 38 35 ↔ 37 36 ↔ 39 37 ↔ 40 38 ↔ 41 39 ↔ 42 40 ↔ 43 41 ↔ 44 42 ↔ 45 43 ↔ 46 44 ↔ 47 45 ↔ 48

2-Hydroxy-2-propan-2-ylbutanedioic acid	<Mapping> AtomMap:BMFYB4DAs012$BMFYB4CAr010$0	3-Methyl-2-oxo-butanoic acid
	3 ↔ 2 4 ↔ 3 5 ↔ 5 6 ↔ 1 7 ↔ 4

2-Hydroxy-2-propan-2-ylbutanedioic acid	<Mapping> AtomMap:BMFYB4DAs012$BMFYS2ESa001$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	1 ↔ 1 2 ↔ 2

@@ Line 3: / Line 3: @@
 |SysName=acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase(thioester-hydrolysing, carboxymethyl-forming)
 |names=&&2-isopropylmalate synthase&&3-carboxy-3-hydroxy-4-methylpentanoate3-methyl-2-oxobutanoate-lyase (CoA-acetylating)&&alpha-isopropylmalate synthetase&&alpha-isopropylmalic synthetase
+}}
+{{Enzyme/Reaction| reaction= CoA + 3-Carboxy-3-hydroxy-4-methyl-pentanoic acid = Acetyl-CoA + 3-Methyl-2-oxo-butanoic acid + H2O
+| list=
+&& BMCCPUAPf023$BMFYS2ESa001$0
+&& BMFYB4DAs012$BMFYB4CAr010$0
+&& BMFYB4DAs012$BMFYS2ESa001$0
 }}

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.3.3.13