Enzyme:3.1.2.4

Revision as of 09:00, 2 February 2009

3-hydroxy-2-methylpropanoyl-CoA hydrolase
Systematic Name	3-hydroxy-2-methylpropanoyl-CoA hydrolase
Common Name	3-hydroxyisobutyryl-CoA hydrolase HIB CoA deacylase

(R)-3-Hydroxy-2-methyl-propanoyl-CoA + H2O => CoA + (R)-3-Hydroxy-2-methyl-propanoic acid
(links: (R) -3-Hydroxy-2-methyl-propanoyl-CoA = CoA + (2R) -3-Hydroxy-2-methylpropanoic acid)

(R) -3-Hydroxy-2-methyl-propanoyl-CoA	<Mapping> AtomMap:BMFYB3CAa003$BMCCPUAPf023$0	CoA
	7 ↔ 1 8 ↔ 2 9 ↔ 3 10 ↔ 4 11 ↔ 5 12 ↔ 6 13 ↔ 7 14 ↔ 8 15 ↔ 9 16 ↔ 10 17 ↔ 11 18 ↔ 12 19 ↔ 13 20 ↔ 14 21 ↔ 15 38 ↔ 32 39 ↔ 33 40 ↔ 35 41 ↔ 34 42 ↔ 36 43 ↔ 37 44 ↔ 38 45 ↔ 39 46 ↔ 40 47 ↔ 41 48 ↔ 42 49 ↔ 43 50 ↔ 44 51 ↔ 45

(R) -3-Hydroxy-2-methyl-propanoyl-CoA	<Mapping> AtomMap:BMFYB3CAa003$BMFYB3CAr002$0	(2R) -3-Hydroxy-2-methylpropanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4

S- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] 3-hydroxypropanethioic acid	<Mapping> AtomMap:BMFYS3HOa008$BMCCPUAPf023$0	CoA
	6 ↔ 1 7 ↔ 2 8 ↔ 3 9 ↔ 4 10 ↔ 5 11 ↔ 6 12 ↔ 7 13 ↔ 8 14 ↔ 9 15 ↔ 10 16 ↔ 11 17 ↔ 12 18 ↔ 13 19 ↔ 14 20 ↔ 15 37 ↔ 32 38 ↔ 33 39 ↔ 35 40 ↔ 34 41 ↔ 36 42 ↔ 37 43 ↔ 38 44 ↔ 39 45 ↔ 40 46 ↔ 41 47 ↔ 42 48 ↔ 43 49 ↔ 44 50 ↔ 45

S- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] 3-hydroxypropanethioic acid	<Mapping> AtomMap:BMFYS3HOa008$BMFYS3CAq008$0	3-Hydroxy-propanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3

S- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] (2S) -3-hydroxy-2-methylpropanethioic acid	<Mapping> AtomMap:BMFYB3CAa007$BMCCPUAPf023$0	CoA
	7 ↔ 1 8 ↔ 2 9 ↔ 3 10 ↔ 4 11 ↔ 5 12 ↔ 6 13 ↔ 7 14 ↔ 8 15 ↔ 9 16 ↔ 10 17 ↔ 11 18 ↔ 12 19 ↔ 13 20 ↔ 14 21 ↔ 15 38 ↔ 32 39 ↔ 33 40 ↔ 35 41 ↔ 34 42 ↔ 36 43 ↔ 37 44 ↔ 38 45 ↔ 39 46 ↔ 40 47 ↔ 41 48 ↔ 42 49 ↔ 43 50 ↔ 44 51 ↔ 45

S- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] (2S) -3-hydroxy-2-methylpropanethioic acid	<Mapping> AtomMap:BMFYB3CAa007$BMFYB3CAr006$0	(2S) -3-Hydroxy-2-methylpropanoic acid
	1 ↔ 3 2 ↔ 2 3 ↔ 1 4 ↔ 4

@@ Line 3: / Line 3: @@
 |SysName=3-hydroxy-2-methylpropanoyl-CoA hydrolase
 |names=&&3-hydroxyisobutyryl-CoA hydrolase&&HIB CoA deacylase
+}}
+{{Enzyme/Reaction| reaction= (R)-3-Hydroxy-2-methyl-propanoyl-CoA + H2O => CoA + (R)-3-Hydroxy-2-methyl-propanoic acid
+| list=
+&& BMFYB3CAa003$BMCCPUAPf023$0
+&& BMFYB3CAa003$BMFYB3CAr002$0
+}}
+{{Enzyme/Reaction| reaction= 3-Hydroxy-propanoyl-CoA + H2O => CoA + 3-Hydroxy-propanoic acid
+| list=
+&& BMFYS3HOa008$BMCCPUAPf023$0
+&& BMFYS3HOa008$BMFYS3CAq008$0
+}}
+{{Enzyme/Reaction| reaction= (S)-3-Hydroxy-2-methyl-propanoyl-CoA + H2O => CoA + (S)-3-Hydroxy-2-methyl-propanoic acid
+| list=
+&& BMFYB3CAa007$BMCCPUAPf023$0
+&& BMFYB3CAa007$BMFYB3CAr006$0
 }}

IDs and Links
IUBMB	EC3
ExPaSy	NiceZyme 3.1.2.4