Enzyme:6.2.1.1

Latest revision as of 06:00, 21 June 2009

acetate:CoA ligase (AMP-forming)
Systematic Name	acetate:CoA ligase (AMP-forming)
Common Name	acetate-CoA ligase acetyl-CoA synthetase acetyl activating enzyme acetate thiokinase acyl-activating enzyme

CoA	<Mapping> AtomMap:BMCCPUAPf023$BMFYS2ESa001$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	1 ↔ 4 2 ↔ 5 3 ↔ 6 4 ↔ 7 5 ↔ 8 6 ↔ 9 7 ↔ 10 8 ↔ 11 9 ↔ 12 10 ↔ 13 11 ↔ 14 12 ↔ 15 13 ↔ 16 14 ↔ 17 15 ↔ 18 32 ↔ 35 33 ↔ 36 34 ↔ 38 35 ↔ 37 36 ↔ 39 37 ↔ 40 38 ↔ 41 39 ↔ 42 40 ↔ 43 41 ↔ 44 42 ↔ 45 43 ↔ 46 44 ↔ 47 45 ↔ 48

ATP	<Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0	AMP
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15

Acetic acid	<Mapping> AtomMap:BMFYS2CA0001$BMFYS2ESa001$1 (2nd)	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	1 ↔ 1 2 ↔ 2

CoA + ATP + Propanoic acid => Propanoyl-CoA + AMP + Pyrophosphate
(links: CoA + ATP + Propanoic acid = Propanoyl-CoA + AMP)

CoA	<Mapping> AtomMap:BMCCPUAPf023$BMFYS3ESa001$0	Propanoyl-CoA
	1 ↔ 5 2 ↔ 6 3 ↔ 7 4 ↔ 8 5 ↔ 9 6 ↔ 10 7 ↔ 11 8 ↔ 12 9 ↔ 13 10 ↔ 14 11 ↔ 15 12 ↔ 16 13 ↔ 17 14 ↔ 18 15 ↔ 19 32 ↔ 36 33 ↔ 37 34 ↔ 38 35 ↔ 39 36 ↔ 40 37 ↔ 41 38 ↔ 42 39 ↔ 43 40 ↔ 44 41 ↔ 45 42 ↔ 46 43 ↔ 47 44 ↔ 48 45 ↔ 49

ATP	<Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0	AMP
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15

Propanoic acid	<Mapping> AtomMap:BMFYS3CA0022$BMFYS3ESa001$0	Propanoyl-CoA
	1 ↔ 1 2 ↔ 2 3 ↔ 3

@@ Line 1: / Line 1: @@
+{{ {{NAMESPACE}}/Header}}
 {{Enzyme
 |ec={{PAGENAME}}
 |SysName=acetate:CoA ligase (AMP-forming)
 |names=&&acetate-CoA ligase&&acetyl-CoA synthetase&&acetyl activating enzyme&&acetate thiokinase&&acyl-activating enzyme
+}}
+{{Enzyme/Reaction| reaction= CoA + ATP + Acetic acid => Acetyl-CoA + AMP + Pyrophosphate
+| list=
+&& BMCCPUAPf023$BMFYS2ESa001$0
+&& BMCCPUAP0022$BMCCPUAP0021$0
+&& BMFYS2CA0001$BMFYS2ESa001$1
+}}
+{{Enzyme/Reaction| reaction= CoA + ATP + Propanoic acid => Propanoyl-CoA + AMP + Pyrophosphate
+| list=
+&& BMCCPUAPf023$BMFYS3ESa001$0
+&& BMCCPUAP0022$BMCCPUAP0021$0
+&& BMFYS3CA0022$BMFYS3ESa001$0
 }}

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.2.1.1