Enzyme:2.3.3.8

Latest revision as of 06:00, 21 June 2009

acetyl-CoA:oxaloacetate C-acetyltransferase[(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
Systematic Name	acetyl-CoA:oxaloacetate C-acetyltransferase[(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
Common Name	ATP citrate synthase ATP-citric lyase ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-->acetyl-CoA](ATP-dephosphorylating) acetyl-CoA:oxaloacetate acetyltransferase (isomerizing ADP-phosphorylating)

ATP	<Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0020$0	ADP
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15

CoA	<Mapping> AtomMap:BMCCPUAPf023$BMFYS2ESa001$0	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	1 ↔ 4 2 ↔ 5 3 ↔ 6 4 ↔ 7 5 ↔ 8 6 ↔ 9 7 ↔ 10 8 ↔ 11 9 ↔ 12 10 ↔ 13 11 ↔ 14 12 ↔ 15 13 ↔ 16 14 ↔ 17 15 ↔ 18 32 ↔ 35 33 ↔ 36 34 ↔ 38 35 ↔ 37 36 ↔ 39 37 ↔ 40 38 ↔ 41 39 ↔ 42 40 ↔ 43 41 ↔ 44 42 ↔ 45 43 ↔ 46 44 ↔ 47 45 ↔ 48

2-Hydroxy-propane-1,2,3-tricarboxylic acid	<Mapping> AtomMap:BMFYB5DAk011$BMFYS4DAp014$1 (2nd)	2-Oxo-butanedioic acid
	3 ↔ 2 4 ↔ 3 5 ↔ 4 6 ↔ 1

2-Hydroxy-propane-1,2,3-tricarboxylic acid	<Mapping> AtomMap:BMFYB5DAk011$BMFYS2ESa001$1 (2nd)	S- [2- [3- [ [ (2R) -4- [ [ [ (2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethyl] ethanethioate
	1 ↔ 1 2 ↔ 2

@@ Line 1: / Line 1: @@
+{{ {{NAMESPACE}}/Header}}
 {{Enzyme
 |ec={{PAGENAME}}
 |SysName=acetyl-CoA:oxaloacetate C-acetyltransferase[(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
 |names=&&ATP citrate synthase&&ATP-citric lyase&&ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-->acetyl-CoA](ATP-dephosphorylating)&&acetyl-CoA:oxaloacetate acetyltransferase (isomerizing&&ADP-phosphorylating)
+}}
+{{Enzyme/Reaction| reaction= ATP + CoA + Citric acid = ADP + Acetyl-CoA + Oxaloacetic acid + Orthophosphate
+| list=
+&& BMCCPUAP0022$BMCCPUAP0020$0
+&& BMCCPUAPf023$BMFYS2ESa001$0
+&& BMFYB5DAk011$BMFYS4DAp014$1
+&& BMFYB5DAk011$BMFYS2ESa001$1
 }}

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.3.3.8