Doc:Tea

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==Classification of Tea <small>分類</small>==
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==Classification of Tea <small>(茶の分類)</small>==
 
===Green Tea (緑茶)===
 
===Green Tea (緑茶)===
 
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==Tea Composition <small>(茶の組成)</small>==
==Tea Composition <small>(組成)</small>==
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==Tea and Human Health <small>(健康情報)</small>==
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==[[Doc:Tea/Consumption|Tea Production/Consumption <small>(茶の生産量、消費量)</small>]]==
 
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==[[Doc:Tea/Health|Tea and Human Health <small>(健康情報)</small>]]==
===Cancer 癌===
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{{Twocolumn|As below, none of the large-scale epidemiological studies showed a significant association of tea intake with a lower risk of cancer<ref name="Borrelli">Borrelli F, Capasso R et al. (2004) "Systematic review: green tea and gastrointestinal cancer risk" Aliment Pharmacol Ther 19:497-510</ref>. However, many case-control studies and cross-sectional studies (up to several hundreds people) show a decrease of the risk of cancer.
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以下のように、いずれの大規模疫学調査においても、お茶を飲む習慣と低い癌リスクの関連は見出されていません<ref name="Borrelli"/>。ただし、多くの症例コントロール研究や横断的研究で癌リスクの低下は報告されています。<br/>
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* Breast cancer 乳がん
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:: Two prospective studies with 35,004 women <ref>Suzuki Y, Tsubono Y et al. (2004) "Gren tea and the risk of breast cancer: pooled analysis of two prospective studies in Japan" Br J Cancer 90:1361-1363</ref> &rarr; no association
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* Gastrointestinal cancer 胃腸がん
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:: Prospective cohort 14873 men and 23667 women <ref name="Nagano">Nagano J, Kono S et al. (2001) "A prospective study of green tea consumption and cancer incidence, Hiroshima and Nagasaki (Japan)" Cancer Causes Control 12:501-508</ref> &rarr; no association
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:: Prospective cohort 11902 men and 14409 women <ref>Tsubono Y, Nishino Y et al. (2001) "Green tea and the risk of gastric cancer in Japan" New Engl J Med 344:632-636</ref> &rarr; no association
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:: Prospective cohort 30370 men and 42481 women <ref>Hoshiyama Y, Kawaguchi T et al. (2002) "A prospective study of stomach cancer death in relation to green tea consumption in Japan" Br J Cancer 87:309-313</ref> &rarr; no association
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:: Prospective cohort 18746 men and 26184 women <ref>Fujino Y, tamakoshi A et al. (2002) "Prospective study of education background and stomach cancer in Japan" Prev Med 35:121-127</ref> &rarr; no association
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* Bladder cancer 膀胱がん
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:: Prospective cohort 14873 men and 23667 women <ref name="Nagano"/> &rarr; no association
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* Cancer incidence がん
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:: Prospective study 38540 people <ref name="Nagano"/> &rarr; no association
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;References
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===Cardiovascular Disease (CVD) 循環器疾患===
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It is often believed that (oolong) tea possesses hypotensive effects.
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After Hertog MG et al.<ref name="Hertog">Hertog MG, Feskens EJ (1993) "Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study" Lancet 342(8878):1007-1011</ref>, flavonoid intakes have been reported to inversely associated with CVDs. In 2008, Hooper et al. performed a comprehensive review of reliable 133 flavonoid trials<ref name="Hooper">Hooper L, Kroon PA, Rimm EB, et al. "Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials" Am J Clin Nutr 88:38–50</ref>, and concluded that
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* flavanol-rich cocoa reduces blood pressure by 6 (systolic) and 3 (diastolic) mm Hg,
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* soy protein, which is rich in isoflavones, reduces LDL cholesterol by 0.2 mmol/L,
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* black tea acutely (not chronic) raises blood pressure by 6 (systolic) and 3 (diastolic) mm Hg, and
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* chocolate acutely (not chronic) increases flow-mediated dilation (FMD) by 4%.
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At least, cocoa and soy (not tea) provide evidence for beneficial effects on CVD. However, it remains unclear whether the effects can be attributed to the specific flavonoid species<ref name="Geleijnse">Geleijnse JM, Hollman PCH (2008) "Flavonoids and cardiovascular health: which compounds, what mechanisms?" Am J Clin Nutr 88:12-13</ref>. A large scale cohort study (34789 men) found no association with flavonoids and CVD <ref name="Rimm">Rimm EB, Katan MB (1996) "Relation between intake of flavonoids and risk for coronary heart disease in male health professionals" Ann Intern Med 125(5):384-389 and Huxley RR, Neil HA (2003) "The relation between dietary flavonol intake and coronary heart disease mortality: a meta-analysis of prospective cohort studies" Eur J Clin Nutr 57:904–908</ref>.
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ウーロン茶は血圧降下に効くと信じられているようです。
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Hertog MGらの研究以後<ref name="Hertog"/>フラボノイドの摂取は循環器疾患に良いとされてきました。
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2008年、Hooperらが信頼できる133 のフラボノイド研究を再調査し以下の結論を導きました<ref name="Hooper"/>。
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* フラバノールが多いココアは血圧を 6 (収縮期)、 3 (拡張期) mm Hg下げる
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* イソフラボンの多い大豆プロテインはLDLコレステロールを 0.2 mmol/L下げる
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* 紅茶は一時的に血圧を 6 (収縮期) 、 3 (拡張期) mm Hg上げる
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* チョコレートは一時的にFMD(血流依存性血管拡張)を4%上げる
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お茶ではなくココアや大豆等がCVDに良い効果を与えることは示されていますが、具体的にフラボノイドが原因かどうかは明らかではありません<ref name="Geleijnse"/>。大規模なコホート研究では (34789 men)フラボノイドと循環器疾患の関係は見出されませんでした<ref name="Rimm"/>。
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;References
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===Obesity 肥満===
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Recently, resveratrol is found to improve obesity.<ref name="Baur">Baur JA et al. Sinclair DA (2006) "Resveratrol improves health and survival of mice on a high-calorie diet" Nature 444:337-342</ref>. Some studies suggest relationship between green tea consumption and reduction in body fat<ref name="Wu">Wu CH, Lu FH et al. (2003) "Relationship among habitual tea consumption, percent body fat, and body fat distribution" Obes Res 11:1088-1095</ref><ref name ="Tian">Tian WX, Li LC et al. (2004) "Weight reduction by Chinese medicinal herbs may be related to inhibition of fatty acid synthase" Life Sci 74:2389-2399</ref>, but clear evidence on body weight control is missing. Since body weight may change for various reasons, it is hard to conduct an epidemiologic study.
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近年レスベラトロールが肥満に効果があるという報告があります<ref name="Baur"/>。緑茶と体脂肪減少の関係を報告する論文もありますが<ref name="Wu"/><ref name="Tian"/>明白な関係はわかりません。体重は様々な要因で変化しやすいので疫学的調査も困難です。
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;References
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Revision as of 16:58, 25 February 2010

Contents

Classification of Tea (茶の分類)

Green Tea (緑茶)

It is non-fermented, i.e., produced by frying or steaming (fixation) the fresh leaves of Camellia sinensis var.sinensis to inactivate polyphenol oxidases. Steaming is common in Japan whereas pan-frying is used in China. Assan (assamica) type contains too much tannins and not suitable for green tea. Almost all green tea is consumed in Japan, Vietnam, China, and Indonesia only.

Black Tea (紅茶)

Unlike green tea, leaves are withered and rolled to crush leaf cells and release polyphenol oxidases. Black tea in India, Sri Lanka, and Kenya is manufactured by a CTC (crushing, tearing, and curling) machine whereas in China an orthodox rotorvane is used. After rolling, leaves are fermented for 0.5 - 3 hours at 25-35 °C with high humidity (>95%). Leaves are fully oxidized and turn golden with floral aroma in this process.

Oolong Tea (烏龍茶)

It is produced by partial fermentation before drying. The process is called green leaf shaking (yaoqing) and green leaf cooling (liangqing), where mildly withered tea leaves are bruised at the edges by hand. Good oolong tea leaves have reddish edges with green centers. It is mainly produced in Fujian, Guangdong (both China), and Taiwan.

Pu-erh Tea (普洱茶)

Raw pu-erh tea is produced by pressing tea leaves and fermenting for years, sometimes for decades. Ripened pu-erh tea, which is more popular, is inoculated with black Aspergillus and fermented under an optimal condition for several months. From Yunnan Pu-erh tea, Aspergillus niger, A. gloucu, and species of Penicillium, Rhizopus, Saccharomyces, and Bacterium are found. A. niger is the most predominant, followed by Saccharomyces spp. [1] Ripened pu-erh tea contains less catechins than raw pu-erh tea, but more gallic acid as the degradation products of catechins (and others). Antioxidant activity is significantly higher for raw pu-erh tea.[2]

  1. Jeng KC, Chen CS, Fang YP, Hou RCW, Chen YS (2007) "Effect of microbial fermentation on content of statin, GABA, and polyphenols in pu-erh tea" J. Agric. Food Chem. 55:8787-8792
  2. Ku KM, Kim J, Park HJ, Liu KH, Lee CH (2010) "Application of Metabolomics in the Analysis of Manufacturing Type of Pu-erh Tea and Composition Changes with Different Postfermentation Year" J. Agric. Food Chem. 58:345-352

Tea Composition (茶の組成)

Catechins

The major phenolics in green tea include catechins (flavan 3-ols). They are (-)-epigallocatechin-3-gallate (EGCG; 59% of total catechins), (-)-epigallocatechin (EGC; 19%), (-)-epicatechin-3-gallate (ECG; 13.6%), and (-)-epicatechin (EC; 6.4%) [1]. Catechins are converted to theaflavins and thearubigins in black tea [2]. A cup of tea may contain 90 mg of EGCG [3], but in human, EGCG is less bioavailable (i.e. little absorbed) than other green tea catechins. However, the bioavailability is different between species and genotypes [4][5].

After drinking tea, the plasma level of catechins reach their peaks (between 1-10 µmol/L) in 2 - 4 h [6]. After 24 h, plasma levels of EGCG and EGC return to baseline, but that of ECG remains elevated in methylated forms[7].

カテキン

緑茶中の主なフェノール化合物はカテキン(フラバン3-オール)で、(-)-エピガロカテキン-3-ガレート (EGCG; 全カテキンの59%), (-)-エピガロカテキン (EGC; 19%), (-)-エピカテキン-3-ガレート (ECG; 13.6%)そして(-)-エピカテキン (EC; 6.4%) [1]です。 紅茶ではカテキンはテアフラビンとテアルビジンに変換されます[2]。 コップ1杯のお茶にはおよそ90 mgのEGCG [3]が含まれますがEGCGは他の茶カテキンに比べ、ヒト体内にあまり吸収されません。 生物学的な利用能力は生物種や遺伝型によって変化します[4][5]

お茶を飲んだ後、血漿中のカテキン濃度は2-4時間でピーク(1-10 µmol/L)に達します[6]。 24時間後には血漿中のEGCG, EGCは初期値に戻りますが、ECGはメチル化された形で残っています[7]

Major Composition (%)[8]
Compound Green tea Black tea Black tea
Infusion (3min)
Proteins 15 15 trace
Amino acids 4 4 3.5
Fiber 26 26 0
Others, carbohydrates 7 7 4
Lipids 7 7 trace
Pigments 2 2 trace
Minerals 5 5 4.5
Phenolic compounds 30 5 4.5
Oxidized phenolics 0 25 4.5
Caffeine

The caffeine content in different types of tea is: black tea > oolong tea > gree tea > fresh tea leaf [9]. More than 200 mg/day caffeine is not advisable and may produce nervousness, sleep disorders, vomits, headaches, epigastric pain, and tachycardia [10].

カフェイン

異なる茶に含まれるカフェインの量は 紅茶>ウーロン茶>緑茶>新鮮な茶葉[9]となります。 200 mg/日以上のカフェイン摂取は、イライラ、不眠、吐き気、頭痛、胃痛や頻脈を引き起こすので薦められません[10]

Caffeine Content in Beverages[11]
Product content (mg /150mL) Product content (mg /150mL)
espresso coffee 108-180 normal coffee 80-115
instant coffee 65 black tea (3min brew) 40-70
oolong tea 18-33 iced tea 29
green tea (3min brew) 15-25 cola soft drink 15-19
hot chocolate 4 cocoa milk shake 3
decaffeinated coffee 1-3 decaffeinated tea 0.6-3
plain chocolate 15 mg/20g milk chocolate 5 mg/20g
References
  1. 1.0 1.1 McKay DL, Blumberg JB (2002) "The role of tea in human health: An update" J Am Coll Nutr 21:1-13
  2. 2.0 2.1 USDA Database for the Flavonoid Contents of Selected Foods, Beltsville 2003
  3. 3.0 3.1 Wu CD, Wei GX (2002) "Tea as a functional food for oral health" Nutrition 18(5):443-444
  4. 4.0 4.1 Kim S, Lee MJ, Hong J (2000) "Plasma and tissue levels of tea catechins in rats and mice during chronic consumption of green tea polyphenols" Nutr Cancer 37:41-48
  5. 5.0 5.1 Loktionov A, Bingham S et al. (1998) "Apolipoprotein E genotype modulates the effect of black tea drinking on blood lipids and blood coagulation factors: A pilot study" Br J Nutr 79:133-139
  6. 6.0 6.1 Yang CS, Chen L et al. (1998) "Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers" Cancer Epidemiol Biomarkers Prev 7:351-354
  7. 7.0 7.1 Higdon JV, Frei B (2003) "Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions" Crit Rev Food Sci Nutr 43:89-143
  8. Belitz DH, Grosch W (1997) "Quimica de los Alimentos" Zaragoza Acribia
  9. 9.0 9.1 Lin Lin YS, Tsai YJ et al. (2003) "Factors affecting the levels of tea polyphenols and caffeine in te a leaves" J Agric Food Chem 51:1864-1873
  10. 10.0 10.1 Varnam AH, Sutherland JP (1994) "Beverages: Technology, Chemistry and Microbiology" Chapman & Hall (London)
  11. Cabrera C, Artacho R, Gimenez R (2006) "Beneficial Effects of Green Tea-A Review" J Am Coll Nutr 25(2):79-99

Tea Production/Consumption (茶の生産量、消費量)

Tea and Human Health (健康情報)

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