Enzyme:2.1.1.13

Revision as of 09:00, 2 February 2009

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
Systematic Name	5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
Common Name	methionine synthase 5-methyltetrahydrofolate-homocysteine S-methyltransferase 5-methyltetrahydrofolate-homocysteine transmethylase N-methyltetrahydrofolate:L-homocysteine methyltransferase N5-methyltetrahydrofolate methyltransferase

L-Homocysteine	<Mapping> AtomMap:BMAAS4SF0002$BMAAS4SF0003$0	(S) -2-Amino-4-methylsulfanylbutanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6

5-Methyl-tetrahydro-folic acid	<Mapping> AtomMap:BMCCPTFOr008$BMCCPTFO0013$0	L-Tetrahydro-folic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 15 ↔ 14 16 ↔ 19 17 ↔ 18 18 ↔ 17 19 ↔ 16 20 ↔ 15 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26

5-Methyl-tetrahydro-folic acid	<Mapping> AtomMap:BMCCPTFOr008$BMAAS4SF0003$0	(S) -2-Amino-4-methylsulfanylbutanoic acid
	14 ↔ 7

L-Homocysteine	<Mapping> AtomMap:BMAAS4SF0002$BMAAS4SF0003$0	(S) -2-Amino-4-methylsulfanylbutanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6

(2S) -2- [ [(4S) -4- [ [(4S) -4- [ [4- [ [(6S) -2-Amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl] methylamino] benzoyl] amino] -5-hydroxy-5-oxopentanoyl] amino] -5-hydroxy-5-oxopentanoyl] amino] pentanedioic acid	<Mapping> AtomMap:BMCCPTFOk010$BMCCPTFOk017$0	(2S) -2- [ [(4S) -4- [ [(4S) -4- [ [4- [ [(6S) -2-Amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl] methylamino] benzoyl] amino] -5-hydroxy-5-oxopentanoyl] amino] -5-hydroxy-5-oxopentanoyl] amino]pentanedioic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 16 ↔ 16 17 ↔ 17 18 ↔ 18 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 27 ↔ 27 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 33 ↔ 32 34 ↔ 37 35 ↔ 36 36 ↔ 35 37 ↔ 34 38 ↔ 33 51 ↔ 50

(2S) -2- [ [(4S) -4- [ [(4S) -4- [ [4- [ [(6S) -2-Amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl] methylamino] benzoyl] amino] -5-hydroxy-5-oxopentanoyl] amino] -5-hydroxy-5-oxopentanoyl] amino] pentanedioic acid	<Mapping> AtomMap:BMCCPTFOk010$BMAAS4SF0003$0	(S) -2-Amino-4-methylsulfanylbutanoic acid
	32 ↔ 7

L-Homocysteine	<Mapping> AtomMap:BMAAS4SF0002$BMAAS4SF0003$0	(S) -2-Amino-4-methylsulfanylbutanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6

5-Methyl-tetrahydro-pteroyl-L-glutamic acid	<Mapping> AtomMap:BMCCPTFOr009$BMCCPTFO0016$0	(2S) -2- [ [4- [(2-Amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl) methylamino] benzoyl] amino] pentanedioic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 15 ↔ 14 16 ↔ 19 17 ↔ 18 18 ↔ 17 19 ↔ 16 20 ↔ 15 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26

5-Methyl-tetrahydro-pteroyl-L-glutamic acid	<Mapping> AtomMap:BMCCPTFOr009$BMAAS4SF0003$0	(S) -2-Amino-4-methylsulfanylbutanoic acid
	14 ↔ 7

@@ Line 3: / Line 3: @@
 |SysName=5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
 |names=&&methionine synthase&&5-methyltetrahydrofolate-homocysteine S-methyltransferase&&5-methyltetrahydrofolate-homocysteine transmethylase&&N-methyltetrahydrofolate:L-homocysteine methyltransferase&&N5-methyltetrahydrofolate methyltransferase
+}}
+{{Enzyme/Reaction| reaction= 5-Methyl-tetrahydro-folic acid + L-Homocysteine => L-Tetrahydro-folic acid + L-Methionine
+| list=
+&& BMAAS4SF0002$BMAAS4SF0003$0
+&& BMCCPTFOr008$BMCCPTFO0013$0
+&& BMCCPTFOr008$BMAAS4SF0003$0
+}}
+{{Enzyme/Reaction| reaction= 5-Methyl-tetrahydro-pteroyl-tri-L-glutamic acid + L-Homocysteine => Tetrahydro-pteroyl-tri-L-glutamic acid + L-Methionine
+| list=
+&& BMAAS4SF0002$BMAAS4SF0003$0
+&& BMCCPTFOk010$BMCCPTFOk017$0
+&& BMCCPTFOk010$BMAAS4SF0003$0
+}}
+{{Enzyme/Reaction| reaction= 5-Methyl-tetrahydro-pteroyl-L-glutamic acid + L-Homocysteine => Tetrahydro-pteroyl-L-glutamic acid + L-Methionine
+| list=
+&& BMAAS4SF0002$BMAAS4SF0003$0
+&& BMCCPTFOr009$BMCCPTFO0016$0
+&& BMCCPTFOr009$BMAAS4SF0003$0
 }}

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.1.13