Enzyme:6.3.2.3

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.2.- Acid--D-amino-acid ligases (peptide synthases).

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.2.3

gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
Systematic Name	gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
Common Name	glutathione synthase glutathione synthetase GSH synthetase

ATP + 5-L-Glutamyl-cysteine + Glycine => ADP + Glutathione + Orthophosphate (links: ATP + (2S) -2-Amino-5- [ [ (2R) -1-hydroxy-1-oxo-3-sulfanylpropan-2-yl] amino] -5-oxopentanoic acid + 2-Amino-acetic acid = ADP + Glutathione)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0020$0 ADP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 (2S) -2-Amino-5- [ [ (2R) -1-hydroxy-1-oxo-3-sulfanylpropan-2-yl] amino] -5-oxopentanoic acid <Mapping> AtomMap:BMAXDP--0002$BMAXTP--0003$0 Glutathione 1 ↔ 7 2 ↔ 8 3 ↔ 9 4 ↔ 10 5 ↔ 11 6 ↔ 1 7 ↔ 2 8 ↔ 3 9 ↔ 4 10 ↔ 5 11 ↔ 6 2-Amino-acetic acid <Mapping> AtomMap:BMAAS2AK0001$BMAXTP--0003$0 Glutathione 1 ↔ 12 2 ↔ 13 3 ↔ 14