Enzyme:1.14.11.2

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.14.-.- Acting on paired donors, with incorporation or reduction of : EC1.14.11.- With 2-oxoglutarate as one donor, and incorporation of one

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.14.11.2

procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase(4-hydroxylating)
Systematic Name	procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase(4-hydroxylating)
Common Name	procollagen-proline dioxygenase protocollagen hydroxylase proline hydroxylase proline,2-oxoglutarate 4-dioxygenase collagen proline hydroxylase

L-Proline + 2-Oxo-glutaric acid + O2 = trans-4-Hydroxy-L-proline + Succinic acid + CO2 (links: (2S) -Pyrrolidine-2-carboxylic acid + 2-Oxo-pentanedioic acid + CO2 = (2S,4R) -4-Hydroxypyrrolidine-2-carboxylic acid + Butanedioic acid + 2-Oxo-pentanedioic acid)
(2S) -Pyrrolidine-2-carboxylic acid <Mapping> AtomMap:BMACPL--0008$BMACPLHO0010$0 (2S,4R) -4-Hydroxypyrrolidine-2-carboxylic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 2-Oxo-pentanedioic acid <Mapping> AtomMap:BMFYS5DAp005$BMFYS4DA0015$0 Butanedioic acid 2 ↔ 4 3 ↔ 3 4 ↔ 2 5 ↔ 1 CO2 <Mapping> AtomMap:BMXXSX--0007$BMFYS5DAp005$0 2-Oxo-pentanedioic acid 1 ↔ 1