Enzyme:1.14.16.6

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.14.-.- Acting on paired donors, with incorporation or reduction of : EC1.14.16.- With reduced pteridine as one donor, and incorporation of one

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.14.16.6

(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygenoxidoreductase (4-hydroxylating)
Systematic Name	(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygenoxidoreductase (4-hydroxylating)
Common Name	mandelate 4-monooxygenase L-mandelate 4-hydroxylase mandelic acid 4-hydroxylase

(S)-2-Hydroxy-2-phenyl-acetic acid + 5,6,7,8-Tetrahydro-biopterin + O2 = (S)-4-Hydroxy-mandelic acid + 6,7-Dihydro-biopterin + H2O (links: 2-Amino-6- [(1R,2S) -1,2-dihydroxypropyl] -6,7-dihydro-1H-pteridin-4-one +  (S) -2-Hydroxy-2-phenyl-acetic acid = 5,6,7,8-Tetrahydro-biopterin +  (S) -4-Hydroxy-mandelic acid)

2-Amino-6- [(1R,2S) -1,2-dihydroxypropyl] -6,7-dihydro-1H-pteridin-4-one <Mapping> AtomMap:BMCCPTPTq010$BMCCPTPTq007$0 5,6,7,8-Tetrahydro-biopterin 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 (S) -2-Hydroxy-2-phenyl-acetic acid <Mapping> AtomMap:BMMCBZ2Ok003$BMMCBZ2Pk004$0 (S) -4-Hydroxy-mandelic acid 1 ↔ 8 2 ↔ 7 3 ↔ 1 4 ↔ 2 5 ↔ 3 6 ↔ 4 7 ↔ 5 8 ↔ 6