Enzyme:2.1.1.13

Upper Levels: EC2.-.-.- Transferases. : EC2.1.-.- Transferring one-carbon groups. : EC2.1.1.- Methyltransferases.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.1.13

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
Systematic Name	5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
Common Name	methionine synthase 5-methyltetrahydrofolate-homocysteine S-methyltransferase 5-methyltetrahydrofolate-homocysteine transmethylase N-methyltetrahydrofolate:L-homocysteine methyltransferase N5-methyltetrahydrofolate methyltransferase

5-Methyl-tetrahydro-folic acid + L-Homocysteine => L-Tetrahydro-folic acid + L-Methionine (links: L-Homocysteine + 5-Methyl-tetrahydro-folic acid = (S) -2-Amino-4-methylsulfanylbutanoic acid + L-Tetrahydro-folic acid)

L-Homocysteine <Mapping> AtomMap:BMAAS4SF0002$BMAAS4SF0003$0 (S) -2-Amino-4-methylsulfanylbutanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 5-Methyl-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOr008$BMCCPTFO0013$0 L-Tetrahydro-folic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 15 ↔ 14 16 ↔ 19 17 ↔ 18 18 ↔ 17 19 ↔ 16 20 ↔ 15 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26 5-Methyl-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOr008$BMAAS4SF0003$0 (S) -2-Amino-4-methylsulfanylbutanoic acid 14 ↔ 7

5-Methyl-tetrahydro-pteroyl-L-glutamic acid + L-Homocysteine => Tetrahydro-pteroyl-L-glutamic acid + L-Methionine (links: L-Homocysteine + 5-Methyl-tetrahydro-pteroyl-L-glutamic acid = (S) -2-Amino-4-methylsulfanylbutanoic acid + (2S) -2- [ [4- [(2-Amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl) methylamino] benzoyl] amino] pentanedioic acid)

L-Homocysteine <Mapping> AtomMap:BMAAS4SF0002$BMAAS4SF0003$0 (S) -2-Amino-4-methylsulfanylbutanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 5-Methyl-tetrahydro-pteroyl-L-glutamic acid <Mapping> AtomMap:BMCCPTFOr009$BMCCPTFO0016$0 (2S) -2- [ [4- [(2-Amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl) methylamino] benzoyl] amino] pentanedioic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 15 ↔ 14 16 ↔ 19 17 ↔ 18 18 ↔ 17 19 ↔ 16 20 ↔ 15 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26 5-Methyl-tetrahydro-pteroyl-L-glutamic acid <Mapping> AtomMap:BMCCPTFOr009$BMAAS4SF0003$0 (S) -2-Amino-4-methylsulfanylbutanoic acid 14 ↔ 7