Enzyme:2.5.1.56

Upper Levels: EC2.-.-.- Transferases. : EC2.5.-.- Transferring alkyl or aryl groups, other than methyl groups. : EC2.5.1.- Transferring alkyl or aryl groups, other than methyl groups.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.5.1.56

phosphoenolpyruvate:N-acetyl-D-mannosamineC-(1-carboxyvinyl)transferase (phosphate-hydrolysing,2-carboxy-2-oxoethyl-forming)
Systematic Name	phosphoenolpyruvate:N-acetyl-D-mannosamineC-(1-carboxyvinyl)transferase (phosphate-hydrolysing,2-carboxy-2-oxoethyl-forming)
Common Name	N-acetylneuraminate synthase (NANA)condensing enzyme N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) NeuAc synthase

N-Acetyl-D-mannosamine + Phosphoenol-pyruvic acid + H2O = N-Acetyl-neuraminic acid + Orthophosphate (links: N-Acetyl-D-mannosamine + 2-Phosphonooxyprop-2-enoic acid = (2S,4S,5R,6R) -5-Acetamido-2,4-dihydroxy-6- [ (1R,2R) -1,2,3-trihydroxypropyl] oxane-2-carboxylic acid)

N-Acetyl-D-mannosamine <Mapping> AtomMap:BMSUM6Ni--02$BMSUM9Ui--01$0 (2S,4S,5R,6R) -5-Acetamido-2,4-dihydroxy-6- [ (1R,2R) -1,2,3-trihydroxypropyl] oxane-2-carboxylic acid 1 ↔ 4 2 ↔ 5 3 ↔ 6 4 ↔ 7 5 ↔ 8 6 ↔ 9 7 ↔ 10 8 ↔ 11 9 ↔ 12 2-Phosphonooxyprop-2-enoic acid <Mapping> AtomMap:BMFYS3CAe021$BMSUM9Ui--01$0 (2S,4S,5R,6R) -5-Acetamido-2,4-dihydroxy-6- [ (1R,2R) -1,2,3-trihydroxypropyl] oxane-2-carboxylic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3