Enzyme:3.5.4.25

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC3.-.-.- Hydrolases. : EC3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. : EC3.5.4.- In cyclic amidines.

IDs and Links
IUBMB	EC3
ExPaSy	NiceZyme 3.5.4.25

GTP 7,8-8,9-dihydrolase (diphosphate-forming)
Systematic Name	GTP 7,8-8,9-dihydrolase (diphosphate-forming)
Common Name	GTP cyclohydrolase II guanosine triphosphate cyclohydrolase II GTP-8-formylhydrolase

GTP + 3 H2O => 2,5-Diamino-6-hydroxy-4-(5'-phosphoribosylamino)-pyrimidine + Formic acid + Pyrophosphate (links: GTP = [(2R,3S,4R,5R) -5- [(2,5-Diamino-4-oxo-1H-pyrimidin-6-yl) amino] -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate + Formic acid)
GTP <Mapping> AtomMap:BMCCPUGU0013$BMMCPYXXe003$0 [(2R,3S,4R,5R) -5- [(2,5-Diamino-4-oxo-1H-pyrimidin-6-yl) amino] -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 9 9 ↔ 8 10 ↔ 7 12 ↔ 11 13 ↔ 12 14 ↔ 13 15 ↔ 14 16 ↔ 15 GTP <Mapping> AtomMap:BMCCPUGU0013$BMFYS1CA0002$0 Formic acid 8 ↔ 1