PKS:An15g04140
From Metabolomics.JP
| Polyketide Top | Species List | UniRef90 Class | UniRef50 Class | Gene Class | Domains (by CDD) |
Domains (by MAPSI) |
| Aspergillus niger CBS 513.88 (GenBank XP_001396949) all species | |||
|---|---|---|---|
| Class | RPKS (length: 2565) all classes Class 39.R-PKS_VI in KS domain phylogeny | Reliability | |
| Product | GeneName | ||
| UniProt,UniRef90 | [1] , [2] | UniRef50 | [3] |
| Domain by MAPSI | KS-AT-DH-ER-KR-ACP | ||
| Domain by CDD | KS-AT-DH-ME-ER-KR-PP | ||
| Domain by ITER-DB | {{{ITERDB}}} | ||
| Estimated Domain | |||
| Description | hypothetical protein An15g04140 [Aspergillus niger] | ||
| Information | Title: strong similarity to polyketide synthase PKS1 - Cochliobolus heterostrophus; Function: PKS1 from C. heterostrophus encodes a multifunctional polyketide synthase with six catalytic domains: beta-ketoacyl synthase-acyltransferase-dehydratase-enoyl reductase-beta-ketoacyl reductase and acyl carrier protein.; Phenotype: PKS1 in race T of the fungal pathogen C. heterostrophus was inactivated by targeted gene disruption-T-toxin production and high virulence were eliminated-indicating that this PKS is required for fungal virulence.; Remark: race T of the fungal pathogen C. heterostrophus may have acquired PKS1 by horizontal DNA-transfer rather than by vertical inheritance from an ancestral strain.; (1.3.1.9); (2.3.1.-)? | ||
| References | |||
| Link | AspGD | ||
This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)