PKS:APar02*

Polyketide Top

Species List

UniRef90 Class

UniRef50 Class

Gene Class

Domains (by CDD)

Domains (by MAPSI)

Aspergillus parasiticus (GenBank AAC41675) all species
Class	NRPKS (length: 2109) all classes   Class in KS domain phylogeny	Reliability	putative
Product	aflatoxin	GeneName	pksL1
UniProt,UniRef90	Q12053 , Q12053	UniRef50	Q12053
Domain by MAPSI	KS-AT-ACP-CYC (notation help / all patterns)
Domain by CDD	KS-AT-PP-TE (notation help / all patterns)
Domain by ITER-DB	{{{ITERDB}}} (notation help / all patterns)
Estimated Domain
Description	polyketide synthase [Aspergillus parasiticus]
Information	AAC41675(Q12053). involved in the synthesis of the polyketide nucleus of aflatoxin from hexanoyl CoA and seven malonates
References	Castoe TA, Stephens T, Noonan BP, Calestani C: A novel group of type I polyketide synthases (PKS) in animals and the complex phylogenomics of PKSs. Gene 392:47-58, 2007 Feng GH, Leonard TJ: Culture conditions control expression of the genes for aflatoxin and sterigmatocystin biosynthesis in Aspergillus parasiticus and A. nidulans. Appl Environ Microbiol 64(6):2275-2277, 1998 Fisch KM, Gillaspy AF, Gipson M, Henrikson JC, Hoover AR, Jackson L, Najar FZ, Wagele H, Cichewicz RH: Chemical induction of silent biosynthetic pathway transcription in aspergillus niger. J Ind Microbiol Biotechnol 36(9):1199-1213, 2009 Valarmathi R, Hariharan GN, Venkataraman G, Parida A: Characterization of a non-reducing polyketide synthase gene from lichen dirinaria applanata. Phytochemistry 70(6):721-729, 2009
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)