PKS:Fung096

Polyketide Top

Species List

UniRef90 Class

UniRef50 Class

Gene Class

Domains (by CDD)

Domains (by MAPSI)

Chaetomium globosum CBS 148.51 (GenBank EAQ92307.1 XP_001219763, EAQ92307.1) all species
Class	NRPKS (length: 2181) all classes   Class 11.NRPKS_I(4a)melanin in KS domain phylogeny	Reliability	putative
Product		GeneName	pks19
UniProt,UniRef90	[1] , [2]	UniRef50	[3]
Domain by MAPSI	KS-AT-ACP-ACP-CYC (notation help / all patterns)
Domain by CDD	KS-AT-PP-PP-TE (notation help / all patterns)
Domain by ITER-DB	{{{ITERDB}}} (notation help / all patterns)
Estimated Domain	SAT-KS-AT-ACP-ACP-TE/CLC
Description	polyketide synthase [Chaetomium globosum CBS 148.51]
Information	Polyketide products biosynthesized by PKS XP_001219763 (CHGG_00542, id in Chaetomium globosum CBS 148.51) in yeast have been identified. A mutation in the TE/CLC domain of XP_001219763 will cause the production of different compounds. XP_001219763 might be functionally equivalent to PKS1 of A.oryzae.
References	Ishiuchi K, Nakazawa T, Ookuma T, Sugimoto S, Sato M, Tsunematsu Y, Ishikawa N, Noguchi H, Hotta K, Moriya H and Watanabe K: Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics. Chembiochem 13(6):846-854, 2012 Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)