PKS:Fung096

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Polyketide Top Species List UniRef90 Class UniRef50 Class Gene Class Domains
(by CDD)
Domains
(by MAPSI)
Chaetomium globosum CBS 148.51 (GenBank XP_001219763) all species
Class NRPKS (length: 2181) all classes   Class 11.NRPKS_I(4a)melanin in KS domain phylogeny Reliability characterized
Product GeneName pks19
UniProt,UniRef90 [1] , [2] UniRef50 [3]
Domain by MAPSI KS-AT-ACP-ACP-CYC

(notation help / all patterns)

Domain by CDD KS-AT-PP-PP-TE

(notation help / all patterns)

Domain by ITER-DB {{{ITERDB}}}

(notation help / all patterns)

Estimated Domain SAT-KS-AT-ACP-ACP-TE/CLC
Description polyketide synthase [Chaetomium globosum CBS 148.51]
Information EAQ92307.1. Polyketide products biosynthesized by PKS XP_001219763 (CHGG_00542, id in Chaetomium globosum CBS 148.51) in yeast have been identified. A mutation in the TE/CLC domain of XP_001219763 will cause the production of different compounds. XP_001219763 might be functionally equivalent to PKS1 of A.oryzae.
References
  • Ishiuchi K, Nakazawa T, Ookuma T, Sugimoto S, Sato M, Tsunematsu Y, Ishikawa N, Noguchi H, Hotta K, Moriya H and Watanabe K: Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics. Chembiochem 13(6):846-854, 2012
  • Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010
Link AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)

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