PKS:ATEG 07500

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Polyketide Top Species List UniRef90 Class UniRef50 Class Gene Class Domains
(by CDD)
Domains
(by MAPSI)
Aspergillus terreus NIH2624 (GenBank XP_001216121) all species
Class NRPKS (length: 1868) all classes   Class 15.NRPKS_I(8)Pigment-2 in KS domain phylogeny Reliability putative
Product GeneName
UniProt,UniRef90 Q0CFN4 , Q8TGD7 UniRef50 Q8TGD7
Domain by MAPSI KS-AT-ACP-ACP-CYC

(notation help / all patterns)

Domain by CDD KS-AT-PP-PP-TE

(notation help / all patterns)

Domain by ITER-DB KS-AT-ACP-ACP-CYC

(notation help / all patterns)

Estimated Domain SAT(?)-KS-AT-PT-ACP-ACP-TE/CLC
Description hypothetical protein ATEG_07500 [Aspergillus terreus NIH2624]
Information "The SAT domain of ATEG_07500.1 is missing from the annotation of Broad Institute. However, the protein sequence of annotated ATEG_07500.1 has high identity/similarity (93%/96%) to a naphthopyrone synthase (BAB88689.1) cloned by Watanabe and Ebizuka. Although no PKS product been isolated, this naphthopyrone synthase has SAT domain.The annotation of ATEG_07500.1 from Broad Institute might be incorrect." [Ahuja, 2012]
References
  • Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012
  • Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010
Link 07500 AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)

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