PKS:Fung054

Gibberella zeae (GenBank AAU10633) all species
Class	NRPKS (length: 2073) all classes Class 15.NRPKS_I(8)Pigment-2 in KS domain phylogeny	Reliability	identified
Product	aurofusarin	GeneName	pks12
UniProt,UniRef90	[1] , [2]	UniRef50	[3]
Domain by MAPSI	KS-AT-ACP-CYC (notation help / all patterns)
Domain by CDD	KS-AT-RPA-PP-TE (notation help / all patterns)
Domain by ITER-DB	KS-AT-ACP-CYC (notation help / all patterns)
Estimated Domain	SAT-KS-AT-PT-ACP-TE/CLC
Description	type I polyketide synthase [Gibberella zeae]
Information	Gibberella zeae is the teleomorph name of Fusarium graminearum
References	Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012 Frandsen RJ, Nielsen NJ, Maolanon N, Sorensen JC, Olsson S, Nielsen J, Giese H: The biosynthetic pathway for aurofusarin in Fusarium graminearum reveals a close link between the naphthoquinones and naphthopyrones, Mol Microbiol, 61(4): 1069-1080, 2006 Frandsen RJ, Schutt C, Lund BW, Staerk D, Nielsen J, Olsson S, Giese H: Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum, J Biol Chem, 286(12): 10419-10428, 2011 Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)