PKS:Fung068

Polyketide Top

Species List

UniRef90 Class

UniRef50 Class

Gene Class

Domains (by CDD)

Domains (by MAPSI)

Chaetomium chiversii (GenBank ACM42403) all species
Class	NRPKS (length: 2138) all classes   Class 08.NRPKS_I_(1)_OAS-Like in KS domain phylogeny	Reliability	identified
Product	radicicol	GeneName	radS2
UniProt,UniRef90	[1] , [2]	UniRef50	[3]
Domain by MAPSI	KS-AT-ACP (notation help / all patterns)
Domain by CDD	KS-AT-PP-TE (notation help / all patterns)
Domain by ITER-DB	{{{ITERDB}}} (notation help / all patterns)
Estimated Domain
Description	RADS2 nonreducing polyketide synthase [Chaetomium chiversii]
Information	Inferred domain architecture: SAT-KS-AT-PT-ACP-TE
References	Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012 Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010 Wang S, Xu Y, Maine EA, Wijeratne EM, Espinosa-Artiles P, Gunatilaka AA, Molnar I: Functional characterization of the biosynthesis of radicicol, an hsp90 inhibitor resorcylic acid lactone from chaetomium chiversii. Chem Biol 15(12):1328-1338, 2008
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)